With just three matches remaining in the league this season, Luciano Spalletti’s men will be keen to continue their unbeaten streak and get all the points available in a bid to confirm their top four spot.
Lecce faces a challenging selection period as they prepare to host the Italian giants, dealing with several critical absences across the pitch.
Both Kialonda Gaspar and Sadik Fofana are sidelined, while Medon Berisha has been ruled out for the remainder of the campaign.
There is also a late fitness cloud over Riccardo Sottil, who remains a major doubt following a persistent muscle problem.
On a more positive note, Lameck Banda, who has been their standout performer this season with seven goal involvements, will continue to start.
He is expected to lead the offensive charge alongside Walid Cheddira as they look to exploit any lapses in the Juventus backline.
Juventus heads into this clash at the Stadio Via del Mare with a nearly full-strength squad, providing a significant boost for their late-season ambitions.
The most notable news is the return of star striker Dusan Vlahovic, who has rejoined full team training and is expected to reclaim his spot in the starting lineup after a lengthy injury absence.
He is joined by Kenan Yildiz and Khephren Thuram, both of whom are available for selection.
However, the squad isn’t entirely clear of issues; Juan Cabal and Arek Milik remain sidelined.
Discipline is also a major concern for the Bianconeri, as key defensive figures Gleison Bremer and Lloyd Kelly, along with midfielder Manuel Locatelli, are all just one yellow card away from suspension.
Michele Di Gregorio is expected to retain his position between the posts even after facing criticism for conceding a soft goal although an error by Bremer led to Juventus falling behind in the first half.