It is a third game in the space of six days for Liverpool and they will be on a high after thumping Galatasaray 4-0 to reach the Champions League quarter-finals.
The performance at Anfield was a big improvement from the 1-1 draw against relegation-threatened Tottenham last Sunday as the Reds missed the chance to go fourth in the table.
Though, playing before Aston Villa and Chelsea this weekend offers Arne Slot’s side the chance to lay down a marker in the battle for Champions League qualification.
Brighton, meanwhile, have responded well since losing to Liverpool in the FA Cup fourth round last month, winning three of their last four matches to allay any fears of relegation and give themselves an outside chance of qualifying for Europe.
Mitoma picked up a knock in the 1-0 loss to Arsenal at the beginning of the month and subsequently missed last weekend’s victory over Sunderland.
Fabian Hurzeler said at the time that the injury was not “big” and Mitoma is in contention to face Liverpool, while Carlos Baleba is also fit.
Mohamed Salah is out for Liverpool after asking to be substituted with an injury in the second half against Galatasaray on Wednesday night.
Joe Gomez may make the bench on Saturday again but is “definitely” not ready to start, according to his manager.
Alexander Isak has returned to individual training but remains absent along with Wataru Endo, Conor Bradley and Giovanni Leoni.